West Nile virus (WNV), a member of the Flavivirus genus, can cause severe neurological disease, long-term morbidity, and death. In the last decade, nearly 30,000 cases of severe WNV infection have been diagnosed in the U.S. Historically, there has been a lack of effective and specific antiviral treatment for flavivirus infection; current treatment...

In the past decade, West Nile Virus (WNV) in the United States has resulted in more than 29,000 diagnosed cases of infection. These infections can lead to severe neurological disease, long-term morbidity, and in some cases even death. There are no effective and specific antiviral treatments for infection by WNV. There are no currently approved...

Because of the obvious cost-effective advantages to producing mammalian proteins in plants, as opposed to conventional mammalian tissue culture, considerable efforts have been expended in the biotech arena to perfect this technology. One of the major challenges is the efficient transient expression of hetero-oligomeric proteins, which currently...