Despite the promise of cholinesterases as effective treatments against nerve-agent intoxication, the practicality of this therapeutic approach depends on the availability of large amounts of these enzymes. Furthermore, these enzymes are required in stoichiometric rather than catalytic quantities. The present invention is a method of making a transgenic...

Most currently available vaccines consist of killed or live-attenuated pathogens delivered by injection. Despite their success in preventing disease, there are compelling conceptual technical and economical reasons to seek alternatives. Subunit vaccines that target the mucosal immune system are considered by many as such alternatives. For example...