This invention provides a novel promoter useful for
obtaining extremely high levels of cellular transcription and translation. As a
result, production of high levels of heterologous proteins is possible.
The significance of this product lies in both the strength
and the specificity of the promoter for transgene expression in plants and plant
tissue as compared to all existing technologies. Research has demonstrated these
outcomes by monitoring the expression of heterologous jellyfish green
fluorescence protein (GFP) using novel promoter and comparing it with levels
expressed from the cauliflower mosaic virus (CaMV) 35S promoter.
This promoter is also very beneficial for use with genes
targeted for expression in plant roots.
Potential Applications
Genetically engineered plants have enhanced protection
against a variety of stresses and pests; improve yield, as well as other
specific traits that enhance the agricultural product.
In particular, this invention enables neutracueticals to be
engineered into plants such that the plant contains enhanced levels of natural
vitamins or other beneficial organic compounds.
Some of the many potential applications include:
- Introduction of enhanced levels of vitamins and minerals
- Design of plants for bioremediation and soil reclamation,
especially for soils contaminated with heavy metals or other chemical
substances
Benefits and Advantages
The invention offers several key benefits including:
- Enhanced promoter strength and specificity – a critical
factor for the successful introduction of any heterologous gene into plants
- Production of high levels of heterologous genes in plants
– the natural result of increased promoter strength and specificity
- Effective expression of plant root genes
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