Infections caused by the Hepatitis C virus (HCV) are very common worldwide (afflicting up to 3% of the population), and chronic infection may develop into cirrhosis and liver cancer. For this reason a vaccine against HCV would have great utility, with the HCV envelope protein 2 (E2) a promising candidate because it can directly bind to a human cell...

Plant viral vectors have great potential for rapid production of important pharmaceutical proteins. High-yield production, however, of hetero-oligomeric proteins that require the expression and assembly of two or more protein subunits often is problematic due to the competing nature of viral vectors derived from the same virus. Researchers at the...