Recent innovations in developing damage tolerance in ceramic composites have focused on three features, i.e. a porous matrix, low bonding strength coatings, and fugitive coatings that ultimately produce a gap between fiber and matrix. There is a lot of research being carried out in the field of ceramics to produce highly porous, and possess high...

Halistatins are highly potent polyether macrolides with anti-mitotic actions that were originally isolated from certain marine sponges. Similar polyether macrolides, such as, Bryostatin 1 (Ph2), Halichondrin B (PC) and its analog, E7389 (Ph 2), are being tested both preclinically and clinically as anti-cancer agents. Halistatin 1 has highly potent...

Halistatins are highly potent polyether macrolides with anti-mitotic actions that were originally isolated from certain marine sponges. Similar polyether macrolides, such as, Bryostatin 1 (Ph2), Halichondrin B (PC) and its analog, E7389 (Ph 2), are being tested both preclinically and clinically as anti-cancer agents. Halistatin 1 has highly potent...