THERAPEUTIC APPLICATIONS Rheumatoid arthritis Possibly other autoimmune diseases, such as, IBD, Crohn’s Disease, Ulcerative Colitis, Atherosclerosis, etc. EFFICACY In the adjuvant induced arthritis model in rats, SNS, dosed orally, reduces dorsoplantar swelling in a dose dependent manner. More significantly, SNS also displays dose...

THERAPEUTIC APPLICATIONS Rheumatoid arthritis Possibly other autoimmune diseases, such as, IBD, Crohn’s Disease, Ulcerative Colitis, Atherosclerosis, etc. EFFICACY In the adjuvant induced arthritis model in rats, SNS, dosed orally, reduces dorsoplantar swelling in a dose dependent manner. More significantly, SNS also displays dose...

SODIUM NARCISTATIN (SNS) A Potent, Orally Bioavailable Anti-Inflammatory Compound With Bone Sparing Activity THERAPEUTIC APPLICATIONS Rheumatoid arthritis Possibly other autoimmune diseases, such as, IBD, Crohn’s Disease, Ulcerative Colitis, Atherosclerosis, etc. EFFICACY In the adjuvant induced arthritis model in rats, SNS, dosed...

The early promise of pancratistatin as a new type of anticancer and antiviral drug led to various preclinical developments. While there have been improvements to the availability of pancratistatin by the development of new horticultural and synthetic approaches, still there is a need for more efficient techniques for the conversion of pancratistatin...

In the early 80s the collection of Pancratium found a very potent anticancer constituent, pancratistatin. Subsequently, the U.S. National Cancer Institute initiated preclinical development of pancratistatin due to its high level of in vitro and in vivo cancer cell growth inhibitory. Unfortunately, the preclinical development slowed by severe supply...